Anti-TOP2A Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-TOP2A Polyclonal Antibody
中文名称： DNA拓普西异构酶Ⅱ抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Human ; Mouse
应用： WB ; IHC
稀释比例： WB 1:2000-5000. IHC 1:25-100.

抗体信息

靶标： TOP2A
别名： DNA topoisomeraseⅡalpha, TOPO II, DNA topoisomerase 2-alpha, DNA topoisomerase II, alpha isozyme, TOP2, TP2A, DNA topoisomerase II 170 kD, DNA topoisomerase II alpha isozyme, DNA Topoisomerase2, TOP 2A, TopII alpha, Topo II alpha, Topoisomerase DNA II alpha 170kDa, Topoisomerase II alpha 170 kDa, TOP2A_HUMAN, Topo IIα, Topo-IIα, Topoisomerase II-α.
背景说明： This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia.
Swiss Prot： P11388
Gene ID： 7153
免疫原： A synthetic peptide of human TOP2A
Public Immunogen Range： 65-115/1531aa
理论分子量： 174/177/182kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。