Anti-GEMIN2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-GEMIN2 Polyclonal Antibody
中文名称： Gem相关蛋白2抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse
应用： WB ; IHC
稀释比例： WB 1:5000-8000. IHC 1:50-200.

抗体信息

靶标： GEMIN2
别名： GEMIN2; SIP1; SIP1-delta; gem-associated protein 2
背景说明： This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
Swiss Prot： O14893
Gene ID： 8487
亚细胞定位： Cytoplasm Nucleus
免疫原： Recombinant protein of human GEMIN2
Public Immunogen Range： 1-280aa
理论分子量： 32kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

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