Anti-NR3C1 Polyclonal Antibody,BR

产品属性  Product Attributes

基本信息

英文名称：Anti-NR3C1 Polyclonal Antibody

中文名称：核受体亚家族3,C组成员1抗体

规格：50ul ; 100ul ; 20ul

宿主：Rabbit

克隆类型：Polyclonal Antibody

亚型：IgG

交叉反应：Human

应用：IHC

稀释比例：IHC 1:50-200.

抗体信息

靶标：NR3C1

别名：GCCR; GCR; GCRST; GR; GRL; glucocorticoid receptor

背景说明：Receptor for glucocorticoids (GC) (PubMed:27120390). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling (PubMed:9590696).Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175).

Swiss Prot：P04150

Gene ID：2908

亚细胞定位：Cytoplasm Mitochondrion Nucleus Nucleus

免疫原：Recombinant protein of human NR3C1

Public Immunogen Range：1-300aa

理论分子量：52/76/61/65/82/86kDa

其它标识

纯化方法：Affinity purification

储存液：PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.

储存条件：Store at -20℃. Avoid freeze/thaw cycles.

产品介绍  Product Introduction

使用前请离心。如有问题请及时联系我们。

Quick spin before use. If you have any questions, please contact us.

注意事项  Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。