Anti-RPSA Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-RPSA Polyclonal Antibody
中文名称： 核糖体蛋白SA抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Rat ; Human预测
交叉反应：： Bird;Chicken;Hamster;Monkey
应用： WB ; IHC
稀释比例： WB 1:5000-8000. IHC 1:50-200.

抗体信息

靶标： RPSA
别名： 37/67 kDa laminin receptor;37LRP;40S ribosomal protein SA;67 kDa laminin receptor;67LR;LAMBR;Laminin receptor;Laminin receptor 1;LamR;LAMR1;LBP/p40;LRP;LRP/LR;NEM/1CHD4;p40;ribosomal protein SA;RPSA
背景说明： Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
Swiss Prot： P08865
Gene ID： 3921
亚细胞定位： Cytoplasm Nucleus Cell membrane
免疫原： A synthetic peptide of human RPSA
Public Immunogen Range： 245-295/295aa
理论分子量： 33kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。