Anti-CGREF1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CGREF1 Polyclonal Antibody
中文名称： EF手域蛋白1的细胞生长调节剂抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： IHC
稀释比例： IHC 1:50-200.

抗体信息

靶标： CGREF1
别名： Cell growth regulator with EF hand domain 1, Cell growth regulator with EF hand domain protein 1, Cell growth regulatory gene 11, Cell growth regulatory gene 11 protein, CGR 11, CGR11, CGRE1_HUMAN, CGREF 1, CGREF1, Hydrophobestin
背景说明： CGREF1 (cell growth regulator with EF-hand domain 1), also known as CGR11, is a 301 amino acid secreted protein that contains two highly conserved calcium binding EF-hand domains, which are required for mediating cell-cell adhesion. Induced by p53, CGREF1 is able to inhibit cell growth in various cell lines. CGREF1 is encoded by a gene located on human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstrωm syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.
Swiss Prot： Q99674
Gene ID： 10669
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of human CGREF1
Public Immunogen Range： 170-220/318aa
理论分子量： 11/31/47kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。