Anti-NALP2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-NALP2 Polyclonal Antibody
中文名称： NLR家族,吡啶结构域包含蛋白2抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： WB ; IHC
稀释比例： WB 1:1000-3000. IHC 1:50-200.

抗体信息

靶标： NALP2
别名： CLR19.9, FLJ20510, Leucine rich repeat and PYD containing protein 2, LRR and PYD domains-containing protein 2, NACHT, NACHT domain, NACHT leucine rich repeat and PYD containing 2, NACHT LRR and PYD domains containing protein 2, NALP2, NALP2_HUMAN, NBS1, NLR family pyrin domain containing 2, NLRP2, Nucleotide binding oligomerization domain leucine rich repeat and pyrin domain containing 2, Nucleotide-binding site protein 1, PAN1, PYPAF2, PYRIN containing APAF1 like protein2, PYRIN domain and NACHT domain-containing protein 1, PYRIN-containing APAF1-like protein 2
背景说明： This gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). Members of this gene family are thought to be important regulators of immune responses. This gene product interacts with components of the IkB kinase (IKK) complex, and can regulate both caspase-1 and NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) activity. The pyrin domain is necessary and sufficient for suppression of NF-kB activity. An allelic variant (rs147585490) has been found that is incapable of blocking the transcriptional activity of NF-kB. Alternative splicing results in multiple transcript variants encoding different isoforms.
Swiss Prot： Q9NX02
Gene ID： 55655
亚细胞定位： Nucleus Cytoplasm
免疫原： A synthetic peptide of human NALP2
Public Immunogen Range： 125-175/1062aa
理论分子量： 96/120kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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