Anti-MEK3 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-MEK3 Polyclonal Antibody
中文名称： 丝裂原活化蛋白激酶MKK3抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse
应用： IHC
稀释比例： IHC 1:50-200.

抗体信息

靶标： MEK3
别名： MAP2K3;MAPKK3;MEK3;MKK3;PRKMK3;SAPKK-2;SAPKK2;mitogen-activated protein kinase kinase 3
背景说明： The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene.
Swiss Prot： P46734
Gene ID： 5606
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of human MEK3
Public Immunogen Range： 225-275/347aa
理论分子量： 36/39kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

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