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Anti-EZH1 Polyclonal Antibody,BR
Anti-EZH1 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-EZH1 Polyclonal Antibody中文名称: 组蛋白赖氨酸N-甲基EZH1抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human ; Mouse
应用: IP ; WB ; IF ; IHC
稀释比例: WB 1:1000-3000. IHC 1:100-300. IF 1:50-200. IP 3-12ug.
抗体信息
靶标: EZH1别名: Enhancer of zeste homolog 1(Drosophila), Enhancer of zeste homolog 1, ENX-2, ENX2, EZH1, EZH1: enhancer of zeste homolog 1 (Drosophila), EZH1_HUMAN, Histone-lysine N-methyltransferase EZH1, KIAA0388
背景说明: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
Swiss Prot: Q92800
Gene ID: 2145
亚细胞定位: Nucleus
免疫原: A synthetic peptide of human EZH1
Public Immunogen Range: 50-100/747aa
理论分子量: 69/77/85kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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