Anti-SOCS-1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-SOCS-1 Polyclonal Antibody
中文名称： 细胞因子信号传导抑制蛋白1抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： IHC
稀释比例： IHC 1:100-300.

抗体信息

靶标： SOCS-1
别名： CIS1; CISH1; JAB; SOCS-1; SSI-1; SSI1; TIP3; TIP-3; suppressor of cytokine signaling 1
背景说明： This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.
Swiss Prot： O15524
Gene ID： 8651
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of human SOCS-1
Public Immunogen Range： 20-70/211aa
理论分子量： 23kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。