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Anti-NALP4 Polyclonal Antibody,BR
Anti-NALP4 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-NALP4 Polyclonal Antibody中文名称: 癌/睾丸抗原58抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human
应用: IHC
稀释比例: IHC 1:50-200.
抗体信息
靶标: NALP4别名: Nucleotide binding oligomerization domain, leucine rich repeat and pyrin domain containing 4, Cancer/testis antigen 58, CLR19.5, CT58, NACHT, leucine rich repeat and PYD containing 4, NACHT, LRR and PYD containing protein 4, NACHT, LRR and PYD domains-containing protein 4, NALP4_HUMAN, NLR family, pyrin domain containing 4, NLRP4, NALP4G, PAAD and NACHT containing protein 2, PAAD and NACHT-containing protein 2, PAN2, PYPAF4, PYRIN and NACHT-containing protein 2, PYRIN containing APAF1 like protein 4, PYRIN-containing APAF1-like protein 4, Ribonuclease inhibitor 2, RNH2
背景说明: May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors. Acts as a negative regulator of the type I interferon signaling pathway by serving as an adapter to promote DTX4-mediated ubiquitination of activated TBK1, and its subsequent degradation. Suppresses NF-kappaB induction by the cytokines TNFA and IL1B, suggesting that it operates at a point of convergence in these two cytokine signaling pathways.
Swiss Prot: Q96MN2
Gene ID: 147945
免疫原: A synthetic peptide of human NALP4
Public Immunogen Range: 510-560/994aa
理论分子量: 56/103/113kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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