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Anti-AIM2 Polyclonal Antibody,BR
Anti-AIM2 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-AIM2 Polyclonal Antibody中文名称: 干扰素诱导蛋白AIM2抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human
应用: WB ; IHC
稀释比例: WB 1:1000-3000. IHC 1:100-300.
抗体信息
靶标: AIM2别名: Absent in melanoma 2, AIM 2, Aim2, AIM2_MOUSE, Interferon-inducible protein AIM2,
背景说明: Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8 (By similarity). Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.
Swiss Prot: O14862
Gene ID: 9447
亚细胞定位: Cytoplasm Nucleus
免疫原: A synthetic peptide of Human AIM2
Public Immunogen Range: 270-320/343aa
理论分子量: 39kDa
其它标识
纯化方法: Octanoic acid-ammonium sulfate precipitation储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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