Anti-DUSP3 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-DUSP3 Polyclonal Antibody
中文名称： 双特异性蛋白磷酸酶3抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： WB
稀释比例： WB 1:1000-3000.

抗体信息

靶标： DUSP3
别名： Dual specificity phosphatase 3, Dual specificity protein phosphatase 3, Dual specificity protein phosphatase VHR, DUS3_HUMAN, DUSP3, Serine/threonine specific protein phosphatase, Vaccinia H1-related phosphatase, Vaccinia virus phosphatase VH1 related, VHR
背景说明： The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1.
Swiss Prot： P51452
Gene ID： 1845
亚细胞定位： Nucleus Cytoplasm Cell membrane
免疫原： Recombinant protein of human DUSP3
Public Immunogen Range： 1-144aa
理论分子量： 16/20kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。