Anti-CDKL1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CDKL1 Polyclonal Antibody
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse ; Human
应用： WB ; IHC
稀释比例： WB 1:1000-3000. IHC 1:50-200.

抗体信息

靶标： CDKL1
别名： CDC 2 related kinase 1, CDC 2 related kinase, CDC2 related kinase 1, CDC2 related kinase, CDK L1, CDKL 1, cdkl1, CDKL1_HUMAN, Cyclin dependent kinase like 1, cyclin-dependent kinase-like 1 (CDC2-related kinase), Cyclin-dependent kinase-like 1, EC 2.7.11.22, KKIALRE, p42, Protein kinase p42 KKIALRE, Serine/threonine protein kinase KKIALRE, Serine/threonine-protein kinase KKIALRE
背景说明： The activation of signal transduction pathways by growth factors; hormones and neurotransmitters is mediated by the MAP kinases ERK 1 and ERK 2. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif. The protein kinase p56 KKIAMRE is distantly related to the MAP kinase group of proteins and is closely related to p42 KKIALRE. KKIAMRE is predominantly expressed in testis; kidney; brain and lung. KKIAMRE contains the conserved MAP kinase dual phosphorylation motif in the sequence Thr-Asp-Tyr and is activated by treatment of cells by EGF. However; unlike other MAP kinases; the EGF-stimulated kinase activity does not require phosphorylation of KKIAMRE and KKIALRE in the Thr-Asp-Tyr motif.
Swiss Prot： Q00532
Gene ID： 8814
亚细胞定位： Cell membrane Cytoplasm
免疫原： A synthetic peptide of Human CDKL1
Public Immunogen Range： 215-265/358aa
理论分子量： 32/42/109kDa

其它标识

纯化方法： Octanoic acid-ammonium sulfate precipitation
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。