Anti-TERF2IP Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-TERF2IP Polyclonal Antibody
中文名称： 多巴胺受体相互作用蛋白5抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human
应用： WB
稀释比例： WB 1:1000-3000.

抗体信息

靶标： TERF2IP
别名： Dopamine receptor interacting protein 5, Dopamine receptor-interacting protein 5, DRIP 5, DRIP5, hRap1, MGC105533, RAP 1, RAP1 homolog, RAP1, yeast, homolog of antibody Repressor/activator protein 1 homolog antibody TE2IP_HUMAN, Telomeric Repeat Binding Factor 2 Interacting Protein, Telomeric repeat-binding factor 2-interacting protein 1, TERF2-interacting protein, TERF2-interacting telomeric protein 1, TRF2 Interacting Telomeric Protein RAP1, TRF2 interacting telomeric RAP1 protein, TRF2-interacting telomeric protein 1, TRF2-interacting telomeric protein
背景说明： Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). In contrast to other components of the shelterin complex; it is dispensible for telomere capping and does not participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair. Instead; it is required to negatively regulate telomere recombination and is essential for repressing homology-directed repair (HDR); which can affect telomere length. Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with TERF2. Independently of its function in telomeres; also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with TERF2 or other factors; and regulates gene expression. When cytoplasmic; associates with the I-kappa-B-kinase (IKK) complex and acts as a regulator of the NF-kappa-B signaling by promoting IKK-mediated phosphorylation of RELA/p65; leading to activate expression of NF-kappa-B target genes.
Swiss Prot： Q9NYB0
Gene ID： 54386
亚细胞定位： Nucleus
免疫原： A synthetic peptide of Human TERF2IP
Public Immunogen Range： 325-375/399aa
理论分子量： 44kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。