Anti-CADM1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CADM1 Polyclonal Antibody
中文名称： 细胞粘附分子1抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse ; Human
应用： WB
稀释比例： WB 1:1000-3000.

抗体信息

靶标： CADM1
别名： BL2;IGSF4;IGSF4A;NECL2;Necl-2;RA175;ST17;SYNCAM;TSLC1;sTSLC-1;sgIGSF;synCAM1;cell adhesion molecule 1
背景说明： Mediates homophilic cell-cell adhesion in a Ca2+-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and NECTIN3 in a Ca2+-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells; may mediate attachment to and promote communication with nerves. CADM1; together with MITF; is essential for development and survival of mast cells in vivo. Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly (By similarity). May be involved in neuronal migration; axon growth; pathfinding; and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.
Swiss Prot： Q9BY67
Gene ID： 23705
亚细胞定位： Cell membrane Cytoplasm
免疫原： A synthetic peptide of Human CADM1
Public Immunogen Range： 65-115/442aa
理论分子量： 37/48/51kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。