Anti-COPS2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-COPS2 Polyclonal Antibody
中文名称： COP9信号小体复合体亚基2抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Monkey ; Rat ; Mouse
应用： WB
稀释比例： WB 1:1000-3000.

抗体信息

靶标： COPS2
别名： COPS2;ALIEN;CSN2;SGN2;TRIP15;COP9 signalosome subunit 2
背景说明： Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.
Swiss Prot： P61201
Gene ID： 9318
亚细胞定位： Nucleus Cytoplasm
免疫原： Recombinant protein of human COPS2
Public Immunogen Range： 1-440aa
理论分子量： 52kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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