Anti-ERI1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-ERI1 Polyclonal Antibody
中文名称： 3-5外切酶1蛋白抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： IHC
稀释比例： IHC 1:50-200.

抗体信息

靶标： ERI1
别名： ERI1, HEXO, THEX1, 3HEXO, ERI1 exoribonuclease 1, 3 5 exonuclease ERI 1, 3 5 exonuclease ERI1, 3 EXO, 3 exoribonuclease, 3 HEXO, 3 histone mRNA exonuclease 1, 3-5 exonuclease eri1, 3-5 exoribonuclease 1, 3EXO, 3HEXO, ERI 1, Eri 1 homolog, Eri-1 homolog, eri1, Eri1 homolog, ERI1_HUMAN, HEXO, Histone mRNA 3 end specific exonuclease, Histone mRNA 3 end specific exoribonuclease, Histone mRNA 3-end-specific exoribonuclease, Histone mRNA 3-exonuclease 1, MGC35395, Protein 3hExo, THEX 1, Three prime histone mRNA exonuclease 1
背景说明： RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.
Swiss Prot： Q8IV48
Gene ID： 90459
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of human ERI1
Public Immunogen Range： 235-285/349aa
理论分子量： 40kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。