Anti-PPID Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PPID Polyclonal Antibody
中文名称： 肽基脯氨酰顺反异构酶D抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： IHC
稀释比例： IHC 1:50-200.

抗体信息

靶标： PPID
别名： 40 kDa peptidyl prolyl cis trans isomerase, 40 kDa peptidyl prolyl cis trans isomerase D, 40 kDa peptidyl-prolyl cis-trans isomerase, Cyclophilin D, Cyclophilin D, Cyclophilin related protein, Cyclophilin-40, Cyclophilin-related protein, Cyclophilin40, CyclophilinD, CYP 40, CYP 40, CYP-40, CYP40, CYP40, CYPD, CYPD, MGC33096, Peptidyl Prolyl Isomerase D, Peptidyl Prolyl Isomerase D, Peptidyl-prolyl cis-trans isomerase D, Peptidylprolyl isomerase D, PPIase, PPIase D, PPID, PPID, PPID_HUMAN, Rotamase, Rotamase D
背景说明： PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control. May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes. May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus. May regulate MYB by inhibiting its DNA-binding activity. Involved in regulation of AHR signaling by promoting the formation of the AHR:ARNT dimer; the function is independent of HSP90 but requires the chaperone activity. Involved in regulation of UV radiation-induced apoptosis. Promotes cell viability in anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma (ALK+ ALCL) cell lines.
Swiss Prot： Q08752
Gene ID： 5481
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of human PPID
Public Immunogen Range： 30-80/370aa
理论分子量： 40kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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