Anti-STX1A Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-STX1A Polyclonal Antibody
中文名称： 突触融合蛋白1抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： IHC
稀释比例： IHC 1:50-200.

抗体信息

靶标： STX1A
别名： HPC 1, Neuron specific antigen HPC1, Neuron-specific antigen HPC-1,
背景说明： Plays an essential role in hormone and neurotransmitter calcium-dependent exocytosis and endocytosis. Part of the SNARE complex composed of SNAP25, STX1A and VAMP2 which mediates the fusion of synaptic vesicles with the presynaptic plasma membrane. STX1A and SNAP25 are localized on the plasma membrane while VAMP2 resides in synaptic vesicles. The pairing of the three SNAREs from the N-terminal SNARE motifs to the C-terminal anchors leads to the formation of the SNARE complex, which brings membranes into close proximity and results in final fusion. Participates in the calcium-dependent regulation of acrosomal exocytosis in sperm. Plays also an important role in the exocytosis of hormones such as insulin or glucagon-like peptide 1.
Swiss Prot： Q16623
Gene ID： 6804
亚细胞定位： Cell membrane Secreted
免疫原： A synthetic peptide of Human STX1A
Public Immunogen Range： 215-265/288aa
理论分子量： 29/33kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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