Anti-LAYN Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-LAYN Polyclonal Antibody
中文名称： 透明质酸受体抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： IHC
稀释比例： IHC 1:25-100.

抗体信息

靶标： LAYN
别名： Layn, E030012M19Rik, Gm511, LAYN_HUMAN
背景说明： Layilin is a recently cloned ～55-kDa membrane-binding partner for talin (Borowsky and Hynes, 1998 ) that is widely expressed in different cell types and tissue extracts. It is found in peripheral ruffles of spreading cells and is recruited to membrane ruffles in cells induced to migrate in in vitro wounding experiments. Layilin colocalizes with talin in ruffles and binds to talin's ～50-kDa head domain (amino acids 280–435). Other parts of talin (the ～220-kDa tail fragment) can bind β-integrin cytoplasmic tails, vinculin, and F-actin and hence form an integrin-cytoskeleton linkage at sites of cell-substratum contact. Layilin's extracellular domain is homologous with the carbohydrate-recognition domains (CRD) of C-type lectins.
Swiss Prot： Q6UX15
Gene ID： 143903
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of Human LAYN
Public Immunogen Range： 40-90/382aa
理论分子量： 25/43kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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