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Anti-GPR143 Polyclonal Antibody,BR
Anti-GPR143 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-GPR143 Polyclonal Antibody中文名称: 眼部白化病相关蛋白OA1/蛋白偶联受体143抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human
应用: IHC
稀释比例: IHC 1:50-200.
抗体信息
靶标: GPR143别名: ALBINISM OCULAR TYPE I, G protein coupled receptor 143, G-protein coupled receptor 143, GP143_HUMAN, GPR143, MOA1, NETTLESHIP FALLS TYPE OCULAR ALBINISM, Ocular albinism type 1 protein, Ocular albinism type 1 protein homolog, Ocular albinism1 Nettleship Falls type
背景说明: Receptor for tyrosine, L-DOPA and dopamine. After binding to L-DOPA, stimulates Ca2+ influx into the cytoplasm, increases secretion of the neurotrophic factor SERPINF1 and relocalizes beta arrestin at the plasma membrane; this ligand-dependent signaling occurs through a G(q)-mediated pathway in melanocytic cells. Its activity is mediated by G proteins which activate the phosphoinositide signaling pathway. Plays also a role as an intracellular G protein-coupled receptor involved in melanosome biogenesis, organization and transport.
Swiss Prot: P51810
Gene ID: 4935
亚细胞定位: Cytoplasm
免疫原: A synthetic peptide of Human GPR143
Public Immunogen Range: 310-360/404aa
理论分子量: 43kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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