Anti-TEAD3 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-TEAD3 Polyclonal Antibody
中文名称： TEA结构域家族成员3抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse
应用： WB
稀释比例： WB 1:1000-3000.

抗体信息

靶标： TEAD3
别名： DTEF 1, DTEF-1, DTEF1, ETFR 1, ETFR1, TEA domain family member 3, TEA domain family member 5, TEAD 3, TEAD-3, Tead3, TEAD3_HUMAN, TEAD5, TEF 5, TEF5, Transcriptional enhancer factor 5, Transcriptional enhancer factor TEF 5 (DTEF 1), Transcriptional enhancer factor TEF 5, Transcriptional enhancer factor TEF-5
背景说明： Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer.
Swiss Prot： Q99594
Gene ID： 7005
亚细胞定位： Nucleus Cytoplasm
免疫原： A synthetic peptide of Human TEAD3
Public Immunogen Range： 1-51/435aa
理论分子量： 48kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。