Anti-SIGLEC7 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-SIGLEC7 Polyclonal Antibody
中文名称： 唾液酸结合性免疫球蛋白样凝集素7抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： IHC
稀释比例： IHC 1:50-200.

抗体信息

靶标： SIGLEC7
别名： AIRM1;CD328;CDw328;D-siglec;QA79;SIGLEC-7;SIGLEC19P;SIGLECP2;p75;p75/AIRM1;sialic acid-binding Ig-like lectin 7
背景说明： Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).
Swiss Prot： Q9Y286
Gene ID： 27036
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of Human SIGLEC7
Public Immunogen Range： 15-65/467aa
理论分子量： 17/41/51kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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