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Anti-ATG4C Polyclonal Antibody,BR
Anti-ATG4C Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-ATG4C Polyclonal Antibody中文名称: 自噬相关蛋白4C抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Mouse ; Human
应用: WB ; IHC
稀释比例: WB 1:2000-5000. IHC 1:50-200.
抗体信息
靶标: ATG4C别名: APG4 autophagy 4 homolog C (S. cerevisiae), APG4 autophagy 4 homolog C, APG4 C, APG4-C, APG4C, ATG 4C, ATG4 autophagy related 4 homolog C (S. cerevisiae), Atg4c, ATG4C_HUMAN, AUT (S. cerevisiae) like 1, cysteine endopeptidase, AUT like 1, cysteine endopeptidase (S. cerevisiae), AUT like 1, cysteine endopeptidase, AUT like 3 cysteine endopeptidase, AUT-like 3 cysteine endopeptidase, AUTL1, AUTL3, Autophagin 3, Autophagin-3, Autophagy related cysteine endopeptidase 3, Autophagy related protein 4 homolog C, Autophagy-related cysteine endopeptidase 3, Autophagy-related protein 4 homolog C, Cysteine protease ATG4C, EC 3.4.22, FLJ14867,
背景说明: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Swiss Prot: Q96DT6
Gene ID: 84938
亚细胞定位: Cytoplasm
免疫原: A synthetic peptide of Human ATG4C
Public Immunogen Range: 405-455/458aa
理论分子量: 52kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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