Anti-CALCOCO2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CALCOCO2 Polyclonal Antibody
中文名称： 含钙结合结构域、coiled-coil结构域蛋白2抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human
应用： WB ; IHC
稀释比例： WB 1:2000-5000. IHC 1:25-100.

抗体信息

靶标： CALCOCO2
别名： CALCOCO2, NDP52, Nuclear domain 10 protein 52, Nuclear dot protein 52
背景说明： Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation. Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens such as Salmonella typhimurium upon entry into the cytosol by targeting LGALS8-associated bacteria for autophagy. Initially orchestrates bacteria targeting to autophagosomes and subsequently ensures pathogen degradation by regulating pathogen-containing autophagosome maturation. Bacteria targeting to autophagosomes relies on its interaction with MAP1LC3A, MAP1LC3B and/or GABARAPL2, whereas regulation of pathogen-containing autophagosome maturation requires the interaction with MAP3LC3C. May play a role in ruffle formation and actin cytoskeleton organization and seems to negatively regulate constitutive secretion.
Swiss Prot： Q13137
Gene ID： 10241
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of Human CALCOCO2
Public Immunogen Range： 75-125/446aa
理论分子量： 43/47/52kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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