Anti-IL17C Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-IL17C Polyclonal Antibody
中文名称： 白介素-17C抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human
应用： WB ; IHC
稀释比例： WB 1:1000-3000. IHC 1:50-200.

抗体信息

靶标： IL17C
别名： Interleukin-17C, IL17C, CX2, IL-17C, IL 17C, IL-21, IL 21, MGC126884, MGC138401, Cytokine CX2, IL17C_HUMAN
背景说明： Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases.
Swiss Prot： Q9P0M4
Gene ID： 27189
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of Human IL17C
Public Immunogen Range： 80-130/197aa
理论分子量： 22kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。