Anti-E2F4 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-E2F4 Polyclonal Antibody
中文名称： 转录因子E2F-4抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human
应用： WB
稀释比例： WB 1:1000-3000.

抗体信息

靶标： E2F/5
别名： E2F 4;E2F transcription factor 4;E2F transcription factor 4 p107/p130 binding;E2F-4;E2F4;E2F4_HUMAN;p107/p130 binding protein;Transcription factor E2F 4;Transcription factor E2F4
背景说明： The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer. [provided by RefSeq, Jul 2008]
Swiss Prot： Q16254
Gene ID： 1874
亚细胞定位： Nucleus
免疫原： A synthetic peptide of Human E2F4
Public Immunogen Range： 340-390/413aa
理论分子量： 44kDa

其它标识

纯化方法： Octanoic acid-ammonium sulfate precipitation
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。