Anti-HTR6 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-HTR6 Polyclonal Antibody
中文名称： 5-羟色胺受体6抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： WB ; IHC
稀释比例： WB 1:1000-3000. IHC 1:50-200.

抗体信息

靶标： HTR6
别名： 5 HT 6;5 HT6;5 HT6R;5 hydroxytryptamine (serotonin) receptor 6 G protein coupled;5 hydroxytryptamine 6 receptor;5 hydroxytryptamine receptor 6;5-HT-6;5-HT6;5-hydroxytryptamine receptor 6;5HT 6;5HT6R_HUMAN;HTR 6;Htr6;Serotonin receptor 6;
背景说明： 5-HT6, a Serotonin Receptor, appears to regulate cholinergic neurotransmission in the brain rather than the expected interaction as a modulator of dopaminergic transmission. This interaction predicts a possible role for 5-HT6 Receptor antagonists in the treatment of learning and memory disorders. The 5-HT6 Receptor is abundant in limbic areas, which participate in the control of mood and emotion. Some antidepressants and antipsychotics are potent 5-HT6 Receptor antagonists, making this gene valuable for the pharmaceutical industry. 5-HT6 may be involved in the pathogenesis of mood disorders, schizophrenia, in Alzheimer's disease. A splice variant that has a 289bp deletion in the transmembrane region IV and the third intracellular loop has been isolated. 5-HT6 Receptor has been reported primarily in striatum of the brain. Expression has also been seen in stomach, spinal cord, and the lymphoid tissues of rats, including peripheral blood lymphocytes, spleen, and thymus. ESTs have been isolated from brain libraries.
Swiss Prot： P50406
Gene ID： 3362
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of Human HTR6
Public Immunogen Range： 235-285/440aa
理论分子量： 47kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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