Anti-APOBEC3D/F Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-APOBEC3D/F Polyclonal Antibody
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： IHC
稀释比例： IHC 1:50-200.

抗体信息

靶标： APOBEC3D/F
别名： A3D;ABC3D_HUMAN;APOBEC3D;APOBEC3DE;APOBEC3E;Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3D;Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3E pseudogene;ARP6;bK150C2.9;BK150C2.9 protein;DNA dC >dU editing enzyme APOBEC 3D;DNA dC->dU-editing enzyme APOBEC-3D;hCG_41704;HCG41704, isoform CRA_b;Probable DNA dC->dU-editing enzyme APOBEC-3D;Apolipoprotein B mRNA editing enzyme, catalytic polypeptide like 3F;ARP8;DNA dC->dU-editing enzyme APOBEC-3F;Induced upon T cell activation;KA6;
背景说明： DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. May inhibit the mobility of LTR and non-LTR retrotransposons.
Swiss Prot： Q96AK3/Q8IUX4
Gene ID： 200316/140564
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of Human APOBEC3D/F
Public Immunogen Range： 220-270/386aa
理论分子量： 9/12/45/47kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

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2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。