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Anti-ALPP/ALPG/ALPI Polyclonal Antibody,BR
Anti-ALPP/ALPG/ALPI Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-ALPP/ALPG/ALPI Polyclonal Antibody规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Mouse ; Rat ; Human
应用: WB ; IHC
稀释比例: WB 1:2000-5000. IHC 1:50-200.
抗体信息
靶标: ALPP/ALPG/ALPI别名: Alkaline phosphatase;Alkaline phosphatase placental;Alkaline phosphatase placental type;Alkaline phosphatase Regan isozyme;ALP;Alp1;ALPP;FLJ61142;Germ-cell alkaline phosphatase;nagao isozyme;OTTHUMP00000164354;PALP;Placental alkaline phosphatase 1;placental heat-stable alkaline phosphatase;placental type;PLAP;PLAP-1;PLAP1;PPB1_HUMAN;Akp5;Alkaline phosphatase;Alkaline phosphatase Nagao isozyme;Alkaline phosphatase placental like;ALP 1;ALP-1;ALP1;ALPG;ALPPL 2;ALPPL;ALPPL2;C77216;D1Ertd816e;GCAP;Germ cell alkaline phosphatase;Nagao isozyme;Placental alkaline phosphatase-like;Placental like alkaline phosphatase;placental-like;PLAP like;PLAP-like;PPBN_HUMAN;Testicular and thymus alkaline phosphatase;Alkaline Phosphatase/ALPP/ALPI
背景说明: ALPP (Alkaline phosphatase placental type; also SEAP, PALP-1 and ALP) is a 66-68 kDa glycoprotein member of the alkaline phosphatase family of molecules. It is principally expressed by 2nd and 3rd trimester synctiotrophoblasts and tumor cells, and represents one of four alkaline phosphatase isozymes. Experimentally, it cleaves phosphate monoesters into alcohol and phosphate. Human ALPP is synthesized as a 535 amino acid (aa) preproprecursor. It contains a 22 aa signal sequence, a 484 mature region (aa 23-506), and a 29 aa C-terminal propeptide that is cleaved to generate a GPI linkage at Asp506. The ALPP gene is highly allelic and may generate three potential splice variants that involve the signal sequence. The ALPP enzyme utilizes one Mg and two Zn ions, and functions as either a homodimer, or a heterodimer with the related Intestinal (ALPI) and Germ cell (GCAP) family members on the cell surface.
Swiss Prot: P05187/P10696/P09923
Gene ID: 250/251/248
亚细胞定位: Cytoplasm
免疫原: A synthetic peptide of Human ALPP/ALPG/ALPI
Public Immunogen Range: 200-250/532aa
理论分子量: 57/58kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。