Anti-TRIB3 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-TRIB3 Polyclonal Antibody
中文名称： Tribbles同系物3抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： IHC
稀释比例： IHC 1:50-200.

抗体信息

靶标： TRIB3
别名： C20orf97;Neuronal cell death inducible putative kinase;Neuronal cell death-inducible putative kinase;NIPK;p65 interacting inhibitor of NF-kappaB;p65-interacting inhibitor of NF-kappa-B;SINK;SKIP 3;SKIP3;TRB 3;TRB-3;TRB3;TRIB 3;Trib3;TRIB3_HUMAN;Tribbles homolog 3;Tribbles pseudokinase 3;Tribbles3;
背景说明： Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity. Inhibits the transcriptional activity of DDIT3/CHOP and is involved in DDIT3/CHOP-dependent cell death during ER stress. Can inhibit APOBEC3A editing of nuclear DNA.
Swiss Prot： Q96RU7
Gene ID： 57761
亚细胞定位： Nucleus Cytoplasm
免疫原： A synthetic peptide of human TRIB3
Public Immunogen Range： 5-55/358aa
理论分子量： 35/39/40kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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