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Anti-CTTN Polyclonal Antibody,BR
Anti-CTTN Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-CTTN Polyclonal Antibody中文名称: 皮层肌动蛋白抗体
规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Mouse ; Rat ; Human
应用: WB ; IHC
稀释比例: WB 1:2000-5000. IHC 1:25-100.
抗体信息
靶标: CTTN别名: Amplaxin;CTTN;EMS 1;EMS1;FLJ34459;Mammary tumor and squamous cell carcinoma associated;Oncogene EMS1;p80/85 src substrate;Src substrate cortactin;SRC8_HUMAN;
背景说明: This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.
Swiss Prot: Q14247
Gene ID: 2017
亚细胞定位: Cytoplasm
免疫原: A synthetic peptide of human CTTN
Public Immunogen Range: 415-465/550aa
理论分子量: 57/61/71kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。