Anti-CTTN Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CTTN Polyclonal Antibody
中文名称： 皮层肌动蛋白抗体
规格： 100ul ; 50ul ; 20ul
宿主： Rabbit
亚型： IgG
交叉反应： Human
应用： IHC-P
稀释比例： IHC-P 1:25-100.

抗体信息

靶标： CTTN
别名： Amplaxin;CTTN;EMS 1;EMS1;FLJ34459;Mammary tumor and squamous cell carcinoma associated;Oncogene EMS1;p80/85 src substrate;Src substrate cortactin;SRC8_HUMAN;
背景说明： This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.
Swiss Prot： Q14247
Gene ID： 2017
亚细胞定位： Cytoplasm
研究领域： 细胞生物学
免疫原： A synthetic peptide of human CTTN 种属同源性预测Public Immunogen Range 415-465/550aa
理论分子量： 57/61/71kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.
运输条件： 冷冻运输 种属同源性预测

产品介绍 Product Introduction

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