Anti-GAD1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-GAD1 Polyclonal Antibody
中文名称： 谷氨酸脱羧酶1抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： IHC
稀释比例： IHC 1:25-100.

抗体信息

靶标： GAD1
别名： glutamate decarboxylase 67, decarboxylase 1, 67 kDa glutamic acid decarboxylase, Glutamate decarboxylase 67 kDa isoform, GAD1, GAD, GAD-67, GAD 67
背景说明： This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
Swiss Prot： Q99259
Gene ID： 2571
亚细胞定位： Cytoplasm Cell membrane
免疫原： A synthetic peptide of human GAD1
Public Immunogen Range： 205-255/594aa
理论分子量： 25/47/67kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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