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- Anti-HLA-DOB Polyclonal Antibody,BR
Anti-HLA-DOB Polyclonal Antibody,BR
Anti-HLA-DOB Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-HLA-DOB Polyclonal Antibody中文名称: HLAⅡ类组织相容性抗原β抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human ; Rat ; Mouse
应用: WB ; IHC
稀释比例: WB 1:1000-3000. IHC 1:50-200.
抗体信息
靶标: HLA-DOB别名: DOB;HLA_DOB;major histocompatibility complex;class II;DO beta
背景说明: HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.
Swiss Prot: P13765
Gene ID: 3112
亚细胞定位: Cytoplasm
免疫原: Recombinant protein of human HLA-DOB
Public Immunogen Range: 1-273aa
理论分子量: 31kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。