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Anti-RAB3A Polyclonal Antibody,BR
Anti-RAB3A Polyclonal Antibody
(订货以英文名为准)猜你喜欢
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产品属性 Product Attributes
基本信息
英文名称: Anti-RAB3A Polyclonal Antibody中文名称: RAB3A,RAS致癌基因家族成员抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human ; Rat ; Mouse
应用: IHC
稀释比例: IHC 1:100-300.
抗体信息
靶标: RAB3A别名: RAB3A,RAB3,RAB3A member RAS oncogene family,RAB3B,RAB3B member RAS oncogene family,RAB3C,RAB3C member RAS oncogene family,RAB3D member RAS oncogene family,RAD3D,Ras related protein Rab 3A,Ras related protein Rab 3B,Ras related protein Rab 3C,Ras related protein Rab 3D,D2 2,Glioblastoma overexpressed,GOV,RAB16
背景说明: Small GTP-binding protein that plays a central role in regulated exocytosis and secretion. Controls the recruitment, tethering and docking of secretory vesicles to the plasma membrane. Upon stimulation, switches to its active GTP-bound form, cycles to vesicles and recruits effectors such as RIMS1, RIMS2, Rabphilin-3A/RPH3A, RPH3AL or SYTL4 to help the docking of vesicules onto the plasma membrane. Upon GTP hydrolysis by GTPase-activating protein, dissociates from the vesicle membrane allowing the exocytosis to proceed. Stimulates insulin secretion through interaction with RIMS2 or RPH3AL effectors in pancreatic beta cells. Regulates calcium-dependent lysosome exocytosis and plasma membrane repair (PMR) via the interaction with 2 effectors, SYTL4 and myosin-9/MYH9. Acts as a positive regulator of acrosome content secretion in sperm cells by interacting with RIMS1. Plays also a role in the regulation of dopamine release by interacting with synaptotagmin I/SYT.
Swiss Prot: P20336
Gene ID: 5864
亚细胞定位: Cytoplasm Cell membrane
免疫原: Recombinant protein of human RAB3A
Public Immunogen Range: 1-220aa
理论分子量: 25kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。