Anti-APLF Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-APLF Polyclonal Antibody
中文名称： Aprataxin和PNKP样因子抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse
应用： WB
稀释比例： WB 1:1000-3000.

抗体信息

靶标： APLF
别名： 2010301N04Rik, AI452191, Aplf, APLF_HUMAN, Aprataxin and PNK-like factor, Apurinic-apyrimidinic endonuclease APLF, C2orf13, PNK and APTX like FHA protein, PNK and APTX-like FHA domain-containing protein, RGD1565557, XIP1, XRCC1 interacting protein 1, XRCC1-interacting protein 1
背景说明： Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage. Together with PARP3, promotes the retention of the LIG4-XRCC4 complex on chromatin and accelerate DNA ligation during non-homologous end-joining (NHEJ).
Swiss Prot： Q8IW19
Gene ID： 200558
亚细胞定位： Nucleus
免疫原： A synthetic peptide of human APLF
Public Immunogen Range： 60-110/511aa
理论分子量： 57kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。