Anti-NOX4 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-NOX4 Polyclonal Antibody
中文名称： NADPH氧化酶4抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Rat ; Human
应用： IHC
稀释比例： IHC 1:50-200.

抗体信息

靶标： NOX4
别名： Kidney oxidase-1, Kidney superoxide-producing NADPH oxidase, KOX 1, KOX, Kox-1, NADPH, NADPH oxidase 4, Nox4, NOX4_HUMAN, Renal NAD(P)H-oxidase, RENOX
背景说明： Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 5 and isoform 6 display reduced activity.
Swiss Prot： Q9NPH5
Gene ID： 50507
亚细胞定位： Cytoplasm Cell membrane Nucleus
免疫原： A synthetic peptide of human NOX4
Public Immunogen Range： 400-450/578aa
理论分子量： 28/32/58/66kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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