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- Anti-ZNF598 Polyclonal Antibody,BR
Anti-ZNF598 Polyclonal Antibody,BR
Anti-ZNF598 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-ZNF598 Polyclonal Antibody中文名称: 锌指蛋白598抗体
规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human ; Mouse
应用: IHC
稀释比例: IHC 1:50-200.
抗体信息
靶标: ZNF598别名: ZNF598,E3 ubiquitin-protein ligase ZNF598,EC 2.3.2.27,Zinc finger protein 598
背景说明: E3 ubiquitin-protein ligase that plays a key role in the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation. Required for ribosomes to terminally stall during translation of poly(A) sequences by mediating monoubiquitination of 40S ribosomal protein RPS10/eS10, RPS20/uS10 and RPS3/uS3. Stalling precludes synthesis of a long poly-lysine tail and initiates the RQC pathway to degrade the potentially detrimental aberrant nascent polypeptide. Also acts as a component of the 4EHP-GYF2 complex, a multiprotein complex that acts as a repressor of translation initiation.
Swiss Prot: Q86UK7
Gene ID: 90850
亚细胞定位: Cytoplasm
免疫原: A synthetic peptide of human ZNF598
Public Immunogen Range: 270-320/904aa
理论分子量: 34/98kDa
其它标识
纯化方法: Octanoic acid-ammonium sulfate precipitation储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。