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Anti-WAC Polyclonal Antibody,BR

Anti-WAC Polyclonal Antibody

(订货以英文名为准)
产品编号:AC61565 品牌:Acmec

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中文名称:
Anti-WAC Polyclonal Antibody
英文名称:
Anti-WAC Polyclonal Antibody
保存条件:
-20℃

产品属性 Product Attributes

基本信息

英文名称: Anti-WAC Polyclonal Antibody
中文名称: WW结构域包含带螺旋线圈的适配蛋白抗体
规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human ; Rat ; Mouse
应用: WB
稀释比例: WB 1:1000-3000.

抗体信息

靶标: WAC
别名: 1110067P07Rik, BA48B24, BA48B24.1, BM 016, FLJ31290, KIAA1844, MGC10753,
背景说明: Acts as a linker between gene transcription and histone H2B monoubiquitination at 'Lys-120' (H2BK120ub1) ref. Interacts with the RNA polymerase II transcriptional machinery via its WW domain and with RNF20-RNF40 via its coiled coil region, thereby linking and regulating H2BK120ub1 and gene transcription ref. Regulates the cell-cycle checkpoint activation in response to DNA damage ref. Positive regulator of amino acid starvation-induced autophagy ref. Also acts as a negative regulator of basal autophagy ref. Positively regulates MTOR activity by promoting, in an energy-dependent manner, the assembly of the TTT complex composed of TELO2, TTI1 and TTI2 and the RUVBL complex composed of RUVBL1 and RUVBL2 into the TTT-RUVBL complex. This leads to the dimerization of the mTORC1 complex and its subsequent activation ref. May negatively regulate the ubiquitin proteasome pathway ref.
Swiss Prot: Q9BTA9
Gene ID: 51322
亚细胞定位: Nucleus Cytoplasm
免疫原: Recombinant protein of human WAC
Public Immunogen Range: 1-210aa
理论分子量: 71/65/59/48kDa

其它标识

纯化方法: Affinity purification
储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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