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- Anti-FBXW4 Polyclonal Antibody,BR
Anti-FBXW4 Polyclonal Antibody,BR
Anti-FBXW4 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-FBXW4 Polyclonal Antibody中文名称: 含F-框WD重复结构域蛋白4抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human ; Rat ; Mouse
应用: WB ; IHC
稀释比例: WB 1:8000-12000. IHC 1:50-200.
抗体信息
靶标: FBXW4别名: FBXW4;DAC;FBW4;FBWD4;SHFM3;SHSF3
背景说明: This gene is a member of the F-box/WD-40 gene family, which recruit specific target proteins through their WD-40 protein-protein binding domains for ubiquitin mediated degradation. In mouse, a highly similar protein is thought to be responsible for maintaining the apical ectodermal ridge of developing limb buds; disruption of the mouse gene results in the absence of central digits, underdeveloped or absent metacarpal/metatarsal bones and syndactyly. This phenotype is remarkably similar to split hand-split foot malformation in humans, a clinically heterogeneous condition with a variety of modes of transmission. An autosomal recessive form has been mapped to the chromosomal region where this gene is located, and complex rearrangements involving duplications of this gene and others have been associated with the condition. A pseudogene of this locus has been mapped to one of the introns of the BCR gene on chromosome 22.
Swiss Prot: P57775
Gene ID: 6468
亚细胞定位: Cytoplasm
免疫原: Recombinant protein of human FBXW4
Public Immunogen Range: 1-293aa
理论分子量: 46kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。