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- Anti-CALR Polyclonal Antibody,BR
Anti-CALR Polyclonal Antibody,BR
Anti-CALR Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-CALR Polyclonal Antibody中文名称: 钙网蛋白抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human ; Rat ; Mouse
应用: WB ; IF ; IHC
稀释比例: WB 1:1000-3000. IHC 1:50-200. IF 1:50-200.
抗体信息
靶标: CALR别名: Autoantigen RO, CALR, CALR protein, CALR_HUMAN, Calregulin, cC1qR, CRP55, CRTC, Endoplasmic reticulum resident protein 60, ERp60, grp60, HACBP, RO, Sicca syndrome antigen A, SSA
背景说明: CALR,also named as grp60, ERp60, HACBP, CRP55, CRTC and Calregulin, belongs to the calreticulin family. It is a molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. CALR is a ER marker. It interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. CALR interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. The MW of CALR migrates aberrantly at 55 kDa by SDS-PAGE. Some study provided that it's a new possibility for CRT-mediated tumor immune prevention and treatment.
Swiss Prot: P27797
Gene ID: 811
亚细胞定位: Cytoplasm
免疫原: Recombinant protein of human CALR
Public Immunogen Range: 1-393aa
理论分子量: 48kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。