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- Anti-NEURL1 Polyclonal Antibody,BR
Anti-NEURL1 Polyclonal Antibody,BR
Anti-NEURL1 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-NEURL1 Polyclonal Antibody规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human ; Mouse
应用: WB
稀释比例: WB 1:1000-3000.
抗体信息
靶标: NEURL1别名: h neu, h neuralized 1, neu, neu 1, Neuralized like protein 1A, NEURL, NEURL1, NEURL1A, RING finger protein 67, RNF67
背景说明: Plays a role in hippocampal-dependent synaptic plasticity, learning and memory. Involved in the formation of spines and functional synaptic contacts by modulating the translational activity of the cytoplasmic polyadenylation element-binding protein CPEB3. Promotes ubiquitination of CPEB3, and hence induces CPEB3-dependent mRNA translation activation of glutamate receptor GRIA1 and GRIA2. Can function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1 (in vitro), thereby regulating the Notch pathway. Acts as a tumor suppressor; inhibits malignant cell transformation of medulloblastoma (MB) cells by inhibiting the Notch signaling pathway.
Swiss Prot: O76050
Gene ID: 9148
亚细胞定位: Cell membrane
免疫原: A synthetic peptide of human NEURL1
Public Immunogen Range: 10-60/574aa
理论分子量: 60/62kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。