Anti-OPRK1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-OPRK1 Polyclonal Antibody
中文名称： kappa型阿片受体抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human
应用： WB ; IHC
稀释比例： WB 1:8000-12000. IHC 1:100-300.

抗体信息

靶标： OPRK1
别名： Kappa type opioid receptor, KOR 1, KOR, Opiate receptor kappa 1, OPRK 1, OPRK, OPRK1, Oprk2, R21, OPRK_HUMAN
背景说明： G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.
Swiss Prot： P41145
Gene ID： 4986
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of human OPRK1
Public Immunogen Range： 330-380/380aa
理论分子量： 33/42kDa

其它标识

纯化方法： Octanoic acid-ammonium sulfate precipitation
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。