Anti-FOXN4 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-FOXN4 Polyclonal Antibody
中文名称： FOXN4蛋白抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： IHC
稀释比例： IHC 1:100-300.

抗体信息

靶标： FOXN4
别名： FLJ35967, Forkhead box N4, Forkhead box protein N4, Forkhead/winged helix transcription factor FOXN4, FOXN4, FOXN4_HUMAN
背景说明： Transcription factor essential for neural and some non-neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4-NOTCH signaling. Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development.
Swiss Prot： Q96NZ1
Gene ID： 121643
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of human FOXN4
Public Immunogen Range： 110-160/517aa
理论分子量： 27/36/55kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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