Anti-APEX1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-APEX1 Polyclonal Antibody
中文名称： APEX核酸酶1抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： IHC
稀释比例： IHC 1:100-300.

抗体信息

靶标： APEX1
别名： APEN;AP endonuclease 1;APE-1;APE;APE1;APEX;APX;HAP1;REF1
背景说明： The APEX gene encodes the major AP endonuclease in human cells. It encodes the APEX endonuclease, a DNA repair enzyme with apurinic/apyrimidinic (AP) activity. Such AP activity sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. The AP sites are the most frequent pre-mutagenic lesions that can prevent normal DNA replication. Splice variants have been found for this gene; all encode the same protein. Disruptions in the biological functions related to APEX are associated with many various malignancies and neurodegenerative diseases.[provided by RefSeq, Dec 2019]
Swiss Prot： P27695
Gene ID： 328
亚细胞定位： Nucleus Cytoplasm
免疫原： Recombinant protein of human APEX1
Public Immunogen Range： 1-319aa
理论分子量： 36kDa

其它标识

纯化方法： Octanoic acid-ammonium sulfate precipitation
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。