Anti-POLR2D Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-POLR2D Polyclonal Antibody
中文名称： 聚合酶II多肽D抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： IHC
稀释比例： IHC 1:100-300.

抗体信息

靶标： POLR2D
别名： HSRBP4, HSRPB4, POLR2D, RNA polymerase II RPB4, RNA polymerase II subunit B4, RPB16
背景说明： DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB4 is part of a subcomplex with RPB7 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity).
Swiss Prot： O15514
Gene ID： 5433
亚细胞定位： Cytoplasm Nucleus
免疫原： Recombinant protein of human POLR2D
Public Immunogen Range： 1-142aa
理论分子量： 16kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。