Anti-CYP4F11 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CYP4F11 Polyclonal Antibody
中文名称： 细胞色素P450家族4F亚家族多肽11抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Rat ; Human
应用： WB ; IHC
稀释比例： WB 1:1000-3000. IHC 1:100-300.

抗体信息

靶标： CYP4F11
别名： Cytochrome P450 4F11, CP4FB_HUMAN, cytochrome P450, family 4, subfamily F, polypeptide 11, cytochrome P450, subfamily IVF, polypeptide 11
背景说明： A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids and their oxygenated derivatives (oxylipins). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes with high efficiency the oxidation of the terminal carbon (omega-oxidation) of 3-hydroxy fatty acids, such as 3-hydroxyhexadecanoic and 3-hydroxyoctadecanoic acids, likely participating in the biosynthesis of long-chain 3-hydroxydicarboxylic acids.Omega-hydroxylates and inactivates phylloquinone (vitamin K1), and menaquinone-4 (MK-4, a form of vitamin K2), both acting as cofactors in blood coagulation . Metabolizes with low efficiciency fatty acids, including (5Z,8Z,11Z,14Z)-eicosatetraenoic acid (arachidonate) and its oxygenated metabolite 8-hydroxyeicosatetraenoic acid (8-HETE) (PubMed:15364545, PubMed:19932081). Catalyzes N- and O-demethylation of drugs such as erythromycin, benzphetamine, ethylmorphine, chlorpromazine, imipramine and verapamil.
Swiss Prot： Q9HBI6
Gene ID： 57834
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of human CYP4F11
Public Immunogen Range： 410-460/524aa
理论分子量： 60kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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