Anti-USP18 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-USP18 Polyclonal Antibody
中文名称： 泛素特异性肽酶18抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： WB
稀释比例： WB 1:1000-3000.

抗体信息

靶标： USP18
别名： 43 kDa ISG15 specific protease;43 kDa ISG15-specific protease;EC 3.1.2.;hUBP43;Interferon Stimulated Gene 43 kD;ISG15 Specific Processing Protease;ISG15-specific-processing protease;ISG43;Ubiquitin Specific Peptidase 18;Ubiquitin Specific Protease 18 43 kD;Ubiquitin Specific Protease 18;Ubl carboxyl terminal hydrolase 18;Ubl carboxyl-terminal hydrolase 18;Ubl thioesterase 18;Ubl thiolesterase 18;Ubp15;UBP18_HUMAN;USP18;
背景说明： The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15.
Swiss Prot： Q9UMW8
Gene ID： 11274
亚细胞定位： Cytoplasm Nucleus
免疫原： Recombinant protein of human USP18
Public Immunogen Range： 1-372aa
理论分子量： 41/43kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。