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Anti-GNA13 Polyclonal Antibody,BR
Anti-GNA13 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-GNA13 Polyclonal Antibody中文名称: 鸟嘌呤核苷酸结合蛋白亚单位α-13抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human ; Rat ; Mouse
应用: WB
稀释比例: WB 1:1000-3000.
抗体信息
靶标: GNA13别名: G alpha 13, GNA13, Guanine nucleotide binding protein alpha 13 subunit, GNA13_HUMAN
背景说明: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (PubMed:21212405, PubMed:19151758, PubMed:16388592). Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF1/p115RhoGEF, ARHGEF11/PDZ-RhoGEF and ARHGEF12/LARG) (PubMed:16388592). GNA13-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1) (PubMed:19151758, PubMed:21212405). Promotes tumor cell invasion and metastasis by activating Rho/ROCK signaling pathway (By similarity). Inhibits CDH1-mediated cell adhesion in process independent from Rho activation (By similarity).
Swiss Prot: Q14344
Gene ID: 10672
亚细胞定位: Cytoplasm
免疫原: Recombinant protein of human GNA13
Public Immunogen Range: 1-350aa
理论分子量: 33/44kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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