Anti-EIF3I Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-EIF3I Polyclonal Antibody
中文名称： 真核翻译起始因子亚单位I抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： WB ; IHC
稀释比例： WB 1:1000-3000. IHC 1:50-200.

抗体信息

靶标： EIF3I
别名： eIF-3-beta;eIF3 beta;eIF3 p36;eIF3-beta;eIF3-p36;eIF3i;EIF3I_HUMAN;EIF3S2;EIF3S2;formerly;Eukaryotic translation initiation factor 3 subunit 2;Eukaryotic translation initiation factor 3 subunit 2 beta;Eukaryotic translation initiation factor 3 subunit I;eukaryotic translation initiation factor 3;subunit 2 (beta;36kD;eukaryotic translation initiation factor 3;subunit 2 beta;36kDa;eukaryotic translation initiation factor 3;subunit 2;formerly;eukaryotic translation initiation factor 3;subunit I;Predicted protein of HQ2242;PRO2242;TGF beta receptor interacting protein 1;TGF-beta receptor-interacting protein 1;TGFbeta receptor interacting protein 1;TGFbeta receptor-interacting protein 1;TRIP 1;TRIP-1;TRIP1;
背景说明： Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
Swiss Prot： Q13347
Gene ID： 8668
亚细胞定位： Cytoplasm
免疫原： Recombinant protein of human EIF3I
Public Immunogen Range： 1-326aa
理论分子量： 37kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。